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Symbol Name ID |
Adam10
a disintegrin and metallopeptidase domain 10 MGI:109548 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | abnormal granulocyte differentiation |
small thymus |
thymus hypoplasia |
enlarged spleen |
increased spleen weight |
spleen hyperplasia |
abnormal definitive hematopoiesis |
abnormal B cell differentiation |
decreased transitional stage T2 B cell number |
increased transitional stage T1 B cell number |
abnormal T cell differentiation |
decreased double-positive T cell number |
myeloid hyperplasia |
decreased erythrocyte cell number |
decreased hematocrit |
decreased hemoglobin content |
increased neutrophil cell number |
absent marginal zone B cells |
increased follicular B cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased T cell number |
increased leukocyte cell number |
increased hematopoietic stem cell number |
abnormal spleen morphology |
increased spleen red pulp amount |
abnormal platelet physiology |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||
| Adam10tm1.1Dhc/Adam10tm1.1Dhc Cd19tm1(cre)Cgn/Cd19+ (conditional) |
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| Adam10tm1.1Khr/Adam10tm1.1Khr Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Adam10tm1Beni/Adam10tm1Beni Tg(Pf4-icre)Q3Rsko/0 (conditional) |
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| Adam10tm1Zhu/Adam10tm1Zhu Tg(Lck-cre)#Zhu/0 (conditional) |
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| Adam10tm1Zhu/Adam10tm1.1Zhu Tg(Lck-cre)#Zhu/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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